Garcinia Mangostana Extract Powder

INSPIRED INGREDIENTS

Garcinia Mangostana
Extract Powder

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Family Name:

Clusiaceae

Common Name:

Purple Mangosteen,
Mangosteen

Extracted Part(S):

Peels

Family Name:

Clusiaceae

Common Name:

Purple Mangosteen,
Mangosteen

Extracted Part(S):

Peels

Wellness Application

Anti-Bacterial

Product Applications

Beverage

Supplement

Active Ingredients:

Not less 1.0% Mangostin
Not less than 25.0% Polyphenols

• α-Mangostin was found to be a potent inhibitor of acid production by S. mutans UA 159, active against mem brane enzymes, including the F(H+)-ATPase and the phosphoenolpyruvate – sugar phosphotransferase system. Specifically cariogenic oral bacteria [1]..
• Due to their microbicidal potential, modified α-mangostin derivatives could be utilized as active anti-microbial agents in materials for the biomedical and food industry [2].
• The obtained results suggest that α-mangostin targets S. epidermidis through multifarious mechanisms, and especially prompts that loss of cytoplasmic membrane integrity leads to rapid onset of bactericidal activity [3].

[1] Phuong T. M.NguyenP.T.M. Nguyen and Robert E.MarquisR.E. Marquis. Antimicrobial actions of α-mangostin against oral streptococci. Canadian Journal of Microbiology. 57(3): 217-225. https://doi.org/10.1139/W10-122

[2] Narasimhan, Srinivasan et al. “Anti-Bacterial and Anti-Fungal Activity of Xanthones Obtained via Semi-Synthetic Modification of α-Mangostin from Garcinia mangostana.” Molecules (Basel, Switzerland) vol. 22,2 275. 12 Feb. 2017, doi:10.3390/molecules22020275

[3] Sivaranjani, Murugesan et al. “Deciphering the Antibacterial Mode of Action of Alpha-Mangostin on Staphylococcus epidermidis RP62A Through an Integrated Transcriptomic and Proteomic Approach.” Frontiers in microbiology vol. 10 150. 6 Feb. 2019, doi:10.3389/fmicb.2019.00150