Active Ingredients: not less than 5% Andrographolides

The A. paniculata ethanol extract inhibited the SRV virus titer similar to the positive control Lamivudine, and it was not toxic to the A459 cell line. Furthermore, low concentration (1 µg/mL) of A. paniculata extract could stimulate lymphocyte cell proliferation about 38% compared to the control lymphocyte cell without any treatment[1].

Andrographolide can modulate the innate and adaptive immune responses by regulating macrophage pheno typic polarization and Ag-specific antibody production [2].

Apart from its anti-inflammatory effects, andrographolide also exhibits immunomodulatory effects by effectively enhancing cytotoxic T cells, natural killer (NK) cells, phagocytosis, and antibody-dependent cell-mediated cytotoxicity (ADCC) [3].